Thursday, October 1
- Pittsburgh Steelers (24) vs. Cleveland Browns (27)
Sunday, October 4
- Indianapolis Colts (30) vs. Washington Commanders (13)
- Dallas Cowboys (34) vs. Houston Texans (30)
- New York Jets (12) vs. Chicago Bears (23)
- New England Patriots (29) vs. Buffalo Bills (26)
- Jacksonville Jaguars (22) vs. Cincinnati Bengals (17)
- Arizona Cardinals (24) vs. New York Giants (36)
- Tennessee Titans (18) vs. Baltimore Ravens (24)
- Los Angeles Rams (24) vs. Philadelphia Eagles (20)
- Green Bay Packers (17) vs. Tampa Bay Buccaneers (14)
- Miami Dolphins (10) vs. Minnesota Vikings (15)
- Kansas City Chiefs (30) vs. Las Vegas Raiders (27)
- Denver Broncos (14) vs. San Francisco 49ers (24)
- Los Angeles Chargers (23) vs. Seattle Seahawks (30)
- Detroit Lions (26) vs. Carolina Panthers (32)
Monday, October 5
- Atlanta Falcons (TBD) vs. New Orleans Saints (TBD)
Upcoming Week 5 Games
Thursday, October 8
- Tampa Bay Buccaneers vs. Dallas Cowboys @ 7:15 PM
Sunday, October 11
- Philadelphia Eagles (+180) vs. Jacksonville Jaguars (-218) @ 8:30 AM
- New York Giants (+142) vs. Washington Commanders (-170) @ 12:00 PM
- Cleveland Browns (+110) vs. New York Jets (-130) @ 12:00 PM
- Indianapolis Colts (+114) vs. Pittsburgh Steelers (-135) @ 12:00 PM
- Houston Texans (-298) vs. Tennessee Titans (+240) @ 12:00 PM
- Cincinnati Bengals (-360) vs. Miami Dolphins (+285) @ 12:00 PM
- Las Vegas Raiders (+154) vs. New England Patriots (-185) @ 12:00 PM
- Minnesota Vikings (-125) vs. New Orleans Saints (+105) @ 12:00 PM
- Chicago Bears (-142) vs. Green Bay Packers (+120) @ 12:00 PM
- Denver Broncos (-185) vs. Los Angeles Chargers (+154) @ 3:05 PM
- Detroit Lions (-250) vs. Arizona Cardinals (+205) @ 3:25 PM
- San Francisco 49ers (+130) vs. Seattle Seahawks (-156) @ 3:25 PM
- Baltimore Ravens (-192) vs. Atlanta Falcons (+160) @ 7:20 PM
Monday, October 12
- Buffalo Bills (+124) vs. Los Angeles Rams (-148) @ 7:15 PM
